Nausea

Nausea is an uncomfortable feeling in the stomach and other parts of the body; a feeling that can sometimes lead to vomiting. It can contribute to wasting syndrome, dehydration, and malnutrition if it is severe. Nausea is commonly associated with cancer and related treatment, HIV/AIDS and related treatment, and vertigo, among other conditions.

Nausea is distinct from vomiting. While we have a good understanding of vomiting, the reality is that we don’t know much about how nausea works. One key to controlling nausea seems to be serotonin and its receptors.

Based on anecdotes and clinical observation, many patients have had success managing nausea with cannabis even though we don’t yet know all the mechanisms by which the endocannabinoid system is involved.

 

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Medical Cannabis Guidelines

While there isn’t a lot of research to back cannabis as a treatment for nausea, there are many anecdotes of patients successfully managing nausea with cannabis. CBD can also mitigate the intoxicating effects of THC, and both cannabinoids have been shown to be helpful.

DOSING STRATEGY

Start low and go slow with THC. Anecdotally, CBD may be more effective at low doses rather than high doses.

Desired Effect

Nausea Relief

Active Compound

CBDA [9], CBD [42],
THC:CBD Balance [11, 57], THC [1, 42, 57]

Delivery Method

Pulmonary, Sublingual
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Desired Effect

Decrease Need for Rx Medication--Nausea

Active Compound

THC:CBD Balance
(Based on clinical observation)

Delivery Method

Pulmonary
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Desired Effect

Appetite Enhancement

Active Compound

THC [1, 14, 62]

Delivery Method

Pulmonary, Sublingual
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