In rheumatoid arthritis, the immune system, which usually protects us by attacking foreign substances like viruses and bacteria, attacks the joints instead. The attack creates inflammation that leads to swelling, pain, and destruction of tissue.
Rheumatoid Arthritis and Your Endocannabinoid System
Medical Cannabis Guidelines
THC can be a helpful medicine, however some patients are sensitive to the intoxicating effects. Including some CBD with the THC can mitigate the intoxication, and makes high-THC medicine more tolerable for some patients while also having anti-inflammatory properties of its own. Anecdotally, whole plant medicine that includes other cannabinoids, terpenes, and flavonoids has been most effective in managing rheumatoid arthritis.
Start low and go slow with THC if you are taking it internally. Topical medicine may be used liberally without intoxication.
Active CompoundTHC [38, 55, 70], THCA , CBD [22, 38, 41],
B-Caryophyllene [54, 55], Myrcene 
Delivery MethodPulmonary, Sublingual, Oral, Topical (localized relief)
Desired EffectInhibit Arthritis Disease Progression
Active CompoundCBD 
Delivery MethodSublingual, Oral, Topical
Desired EffectPain Relief
Delivery MethodPulmonary, Sublingual, Oral
Medicinal cannabis is unique because dosing is patient-centered, self-titrated, and takes time for patients to find the right dose where therapeutic effects are maximized while adverse effects minimized.